German-Wide Analysis of the Prevalence and the Propagation Factors of the Zoonotic Dermatophyte .

For about 10 years, a new variant of the pathogen () has appeared in Germany, characterized by a previously unobserved culture phenotype with a strong yellow reverse. A few studies suggest that this new variety is now the most common zoophilic dermatophyte in Germany. The guinea pig is the main carrier.

Evaluating sphingosine and its analogues as potential alternatives for aggressive lymphoma treatment.

Background: Ceramide (Cer) and sphingosine (Sph) interfere with critical cellular functions relevant for cancer progression and cell survival. While Cer has already been investigated as a potential drug target for lymphoma treatment, information about the potency of sphingosine is scarce. The aim of this study therefore was to evaluate Sph and its synthetic stereoisomer L-threo-sphingosine (Lt-Sph) as potential treatment options for aggressive lymphomas.