Publications by authors named "Max B Giesken"
Objective: Tectal plate gliomas are rare, slow-growing tumors of the midbrain that are discovered predominantly in the pediatric population. Because of their indolent nature, treatment mainly consists of observation and management of hydrocephalus. Unfortunately, a subset of tectal gliomas may exhibit tumor enlargement and disease progression.
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- Pilocytic astrocytomas are the most common low-grade glioma in children, and this study reviews the top 100 most cited publications to understand their molecular and clinical features.
- The analysis found that half of the articles were basic science, a third clinical, and a smaller portion were reviews; most citations were for research on BRAF/MAPK pathways and treatment options.
- The study highlights an upward trend in research over the past 30 years, with a focus on targeted therapies and identifying new cellular pathways for future investigations.