Publications by authors named "Mavluda Makhmudova"

Article Synopsis
  • - The study compared two WHO-recommended treatments for rifampin- or multidrug-resistant tuberculosis: a shorter regimen lasting 9-12 months and a longer individualized regimen of at least 20 months, using data from various observational studies.
  • - Results showed that the shorter regimen had a higher overall treatment success rate (80.0% vs. 75.3%) and significantly less patient loss to follow-up, though it had a slightly higher risk of treatment failure or relapse, especially in patients with resistance to certain medications.
  • - The findings suggest that while the shorter regimen is more effective in maintaining patient engagement, there is a need for better drug susceptibility testing to ensure appropriate treatment, particularly for those with medication resistance. *
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New drugs and shorter treatments for drug-resistant tuberculosis (DR-TB) have become available in recent years and active pharmacovigilance (PV) is recommended by the World Health Organization (WHO) at least during the early phases of implementation, with active drug safety monitoring and management (aDSM) proposed for this. We conducted a literature review of papers reporting on aDSM. Up to 18 April, 2019, results have only been published from one national aDSM programme.

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Background: There are very few studies on reasons for loss to follow-up from TB treatment in Central Asia. This study assessed risk factors for LTFU and compared their occurrence with successfully treated (ST) patients in Tajikistan.

Methods: This study took place in all TB facilities in the 19 districts with at least 5 TB patients registered as loss to follow-up (LTFU) from treatment.

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Background: Tajikistan National TB Control Program.

Objective: (1) To identify the main obstacles to increasing TB Detection in Tajikistan. (2) To identify interventions that improve TB detection.

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