Publications by authors named "Mauro Pinelli"

Article Synopsis
  • The study investigates the effects of low- and high-dose rosuvastatin on the expression of two important proteins, ABCA1 and ABCG1, which help reduce cholesterol in atherosclerotic plaques in patients with severe carotid artery stenosis.
  • Results showed that both doses of rosuvastatin led to lower levels of ABCA1 mRNA, but unexpectedly, high-dose treatment increased ABCA1 protein levels while having no significant effect on ABCG1 protein.
  • The findings suggest that high-dose rosuvastatin might enhance ABCA1 protein in a way that is independent of changes in cholesterol levels, possibly involving regulation by the microRNA miR-33b-5
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Sexual abuse, even when it occurs during childhood, may manifest symptoms only in adolescence by the effect of the resignifcation of infantile sexuality, characteristic of that vital moment. In cases of child sexual abuse, in the face of the disruption of impulses and identifcations that occurs in adolescence, there can be trauma that limits the possibilities of processing the psychic apparatus, even in the course of a psychotherapeutic treatment. The acting out reveals itself in transference, it calls for the analyst to relocate the suffering of his patient.

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