Reliability of captopril renography in patients under chronic therapy with angiotensin II (AT1) receptor antagonists.

Unlabelled: Captopril renography is a reliable, widely used test for the functional diagnosis of renovascular hypertension. Well-recognized drawbacks of the procedure include reduced accuracy in patients with bilateral disease or renal impairment as well as the possible interference from concurrent antihypertensive medication (diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, calcium channel blockers). Currently, no data exist regarding the reliability of captopril renography in patients with renovascular hypertension evaluated while they are under chronic treatment with angiotensin II (AT1) receptor antagonists (Sartans).