[Taste sensitivity diminution in hyperglycemic type 2 diabetics patients].

Objective: To determine the relationship between fasting blood glucose (FBG) values and gustatory sensitivity alterations in type 2 diabetic patients (DM2) without peripheral neuropathy (PNP).

Methods: Assessment of the strength of association between FBG and detection and recognition taste thresholds for the four primary tastes measured by chemical gustometry were performed in 140 DM2 without PNP with evolution < 10 years.

Results: FBG values above 7.

Fibrinogen is associated with silent myocardial ischaemia in type 2 diabetes mellitus.

Objective: Because traditional risk factors only partially explain coronary events, it is necessary to search for new ones like fibrinogen which has been related with coronary disease in healthy middle-aged adults. We attempted to determine the impact of fibrinogen on silent myocardial ischaemia (SMI) in diabetic patients.

Methods And Results: In a cross-sectional study, 134 type 2 diabetes patients with no history of cardiovascular disease were assessed for SMI.

[Migraine. Review of physiopathogeny and future alternative therapy].

This work examines recent discoveries in physiopathogenesis, focusing on the combination of sequential events involved in migraine origin. Recent facts concerning active intestinal peptide, substance P, histamine, HI and H3 receptors, and H3-receptor agonists, all neuromodulators having an intimate relations ship with migraine were examined. Present-day recommended treatment, with an efficacy of barely 70%, and reasons for its poor performance were described.