Publications by authors named "Mauro Cesar Cafundo de Morais"
Mosquitoes (Diptera: Culicidae) comprise over 3500 global species, primarily in tropical regions, where the females act as disease vectors. Thus, identifying medically significant species is vital. In this context, Wing Geometric Morphometry (WGM) emerges as a precise and accessible method, excelling in species differentiation through mathematical approaches.
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- Two alkaloids, pterogynine (PGN) and pterogynidine (PGD), from the Brazilian plant Pterogyne nitens were found to induce programmed cell death (apoptosis) in human breast cancer cells.
- The study involved testing these compounds on a specific human breast cancer cell line (ZR-7531) with varying concentrations (0.25-10 mM) and analyzing the results using different assays, including Hoechst and annexin V.
- The findings highlight that while both PGN and PGD effectively kill cancer cells in vitro, the Hoechst assay effectively distinguishes between late apoptosis and necrosis, which the annexin V assay could not.