Publications by authors named "Mauro Brulatti"
Purpose: Stratifying patients defective in mismatch repair (dMMR) with high microsatellite instability (MSI-H) in colorectal cancer (CRC) is of increasing relevance and may provide a more tailored approach to CRC adjuvant therapy. Here, we describe the discovery of a new MSI marker for colorectal cancer located in the 3'-untranslated region (3'UTR, T20 mononucleotide repeat) of the metallothionein 1X gene (MT1XT20).
Methods: We studied 340 consecutive CRCs using three multiplexed polymerase chain reactions amplifying BAT25, BAT26, TGFBR2, MybT22, BAT40, MT1XT20, NR21, NR24, CAT25, D2S123, D5S346, D17S250, D18S58, CSF1PO, D7S820, and D18S51.
Conversion rate in laparoscopic cholecystectomy: evolution from 1993 and current state.
J Laparoendosc Adv Surg Tech A
April 2003
The definition of difficult laparoscopic cholecystectomy (LC) is inconsistent. The aim of this study was to analyze the factors that make LC difficult to perform and determine ways to avoid conversion, based on our series. All patients who underwent LC or open cholecystectomy (OC) between January 1993 and December 2001 in our division of general surgery were the subject matter of this study.
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- Laparoscopic gastric banding is an effective obesity treatment, but it has complications like slippage and gastric erosion, leading to the development of various technical modifications to reduce risks but sometimes causes dysphagia (difficulty swallowing).
- A new technique was tested, using a band placed around the esophagus to expand the dysphagia effect without fixation stitches; 80 patients underwent this procedure, with a few complications, such as slippage and an esophageal issue requiring a band replacement.
- Over 24 months, patients showed weight loss and improved eating habits, as the technique encouraged them to chew more and eat smaller portions to avoid dysphagia, demonstrating its potential benefits when properly applied.
Background And Purpose: Twenty years after the first report of laparoscopic appendectomy (LA), its role in the treatment of appendicitis is still under debate. We report herein a retrospective analysis of our cases of LA in the last 5 years, during which we adopted a policy of an almost uniform laparoscopic approach on a rather selected population composed mainly of women with acute or recurrent lower quadrant abdominal pain.
Patients And Methods: Laparoscopic appendectomy was performed on 33 male and 98 female patients.