Publications by authors named "Mauro Aquilini"
Article Synopsis
- Obstructive sleep apnea syndrome (OSAS) involves repeated airway collapses during sleep, leading to intermittent hypoxia and chronic inflammation that can damage neurons and impair cognitive function.
- Patients with OSAS show increased serum levels of brain-derived neurotrophic factor (BDNF), which is linked to neuroprotection and cognitive health, suggesting a potential protective response against neuronal damage.
- Higher BDNF levels correlate with less cognitive impairment in OSAS patients, and treatment with CPAP (a non-invasive ventilation method) can improve cognitive outcomes.
Introduction: Obstructive sleep apnea syndrome (OSAS) has been shown to be an important risk factor for ischaemic cerebral disease. Specific Doppler parameters may be used to measure cerebral vascular dynamics opening the door to new markers/predictors of risk. The objective of our study was to shed light on how the treatment of OSA with continuous positive airway pressure (CPAP) may have an impact on these parameters and, consequently, lower the risk of cerebral ischemic events in these patients.
View Article and Find Full Text PDFIn the early stages of bronchial asthma, it is frequent to find subjects with a positive history and an FEV1 or FEV1/FVC > 80% of the predicted value. This study investigated if the test of reversibility showed a reversible airway obstruction (RAO) in 291 subjects with the above clinical and functional features. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and expiratory flows (PEF, MEF50, FEF(25-75)) were registered before and 20 minutes after salbutamol administration (200 mcg by MDI).
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