Publications by authors named "Maurizio Fraulo"
Article Synopsis
- A study from 2015 examined Toxocara seroprevalence in Serbia with samples from 40 children and 298 adults, revealing an overall seroprevalence of 23.5%.
- The results showed no significant age or regional differences in seroprevalence, but adult women were more reactive than men, and specific activities like spending time in parks and having nail-biting habits increased infection risks.
- The research assessed potential reasons for these differences and discussed the medical, veterinary, and economic implications of Toxocara as a soil-transmitted zoonosis.
During the years 2012-2014, a total of 158 outdoor dogs from Pančevo and Đurđevo (northern Serbia) and Niš and Prokuplje (southern Serbia) were submitted to molecular analyses (PCR and sequencing) for canine babesioses. An overall prevalence of 21.5% was found, due to the species Babesia sp.
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- Cercopithifilaria bainae is a filarial parasite found in dogs and ticks worldwide, but it's generally considered of "minor importance" in veterinary medicine compared to other similar parasites.
- The study reports the first known case of systemic health issues in a dog linked to C. bainae infection, presenting symptoms like chronic polyarthritis and joint pain, despite normal blood tests and X-rays.
- Despite identifying the parasites in the dog's joint fluid, traditional treatments failed to alleviate the condition, highlighting the need for more research on C. bainae and its potential impact on canine health.
A new formulation (NF) of subcutaneous (sc) interferon (IFN) β-1a was developed in an attempt to improve injection tolerability and immunogenicity. We compared antiviral and IFNβ-stimulated gene (ISG) activities of IFNβ-1a sc NF with IFNβ-1a sc original formulation and IFNβ-1b sc. When equivalent unit amounts were compared, the IFNβ formulations demonstrated similar antiviral activity and induced similar levels of ISG mRNA.
View Article and Find Full Text PDFGiven the growing evidence for a role of interleukin-32 (IL-32) in the immune response to HIV-1 infection and its interplay with type I and III interferons (IFNs), we studied the gene expression of IL-32 isoforms (α and nonα) in untreated chronically HIV-1-infected patients and in gender- and age-matched healthy individuals. To further characterize both the anti-HIV properties of IL-32 and the cytokine's relationship with host antiviral innate immune responses, we evaluated whether IL-32 can induce ex vivo the expression of antiviral IFN-induced genes (ISGs), namely myxovirus resistance A (MxA), and apolipoprotein B mRNA-editing enzyme catalytic (APOBEC)3G and APOBEC3F. We also investigated whether in vivo IL-32 (α and nonα) mRNA levels were correlated with those of MxA and APOBEC3G/3F.
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