A Fast-Forward Dilute-and-Shoot Multielement Method for Analysis of 33 Elements in Human Whole Blood, Serum, and Urine by Inductively Coupled Plasma Mass Spectrometry: A Streamlined Approach for Clinical Diagnostic and Biomonitoring.

The analysis of toxic and essential elements in human matrices is used in clinical diagnostics and for biomonitoring of different populations to study related health outcomes. This work aimed to develop fast and reliable methods for the analysis of a broad range of elements in liquid human matrices, such as whole blood, serum, and urine, with a similar setup for the three matrices and different analysis needs. An easy and fast-forward dilute-and-shoot method for 33 elements (i.

Isotope ratio measurements with a fully simultaneous Mattauch-Herzog ICP-MS.

A fully simultaneous ICP-MS, based on a compact Mattauch-Herzog geometry with a permanent magnet and a large, spatially resolving semiconductor ion detector covering the complete inorganic relevant mass range from (6)Li to (238)U in a single measurement, has been used to determine isotope ratios and assess achievable isotope ratio precisions. Measurements of the (235/238)U isotopic ratio, chosen as example for an isotopic system with a disparate isotope ratio, yielded a precision of 0.05 % relative.