Publications by authors named "Maurice J Turner"
J Am Chem Soc
November 2010
Article Synopsis
- N-glycosylation is a crucial post-translational modification that occurs in the endoplasmic reticulum, affecting protein folding and interactions within the ER network.
- Previous studies indicated that just three sugar residues attached to proteins can significantly enhance their folding speed and stability, even if only one sugar is present.
- Experimental and computational analyses using the Pin WW domain revealed that N-glycosylation's effects on protein stability and folding rate are not universal, with varying impacts depending on the specific protein structure and environment.
