Publications by authors named "Maurice Hirst"

Article Synopsis
  • Purpose of the study included assessing the antioxidant activity of Pycnogenol, its effects on lens integrity in organ culture, and its potential to reduce damage in diabetic cataract models.
  • Various methods such as antioxidant assays and lens incubation with glucose were employed, alongside monitoring diabetic rats over 12 weeks to evaluate the impact of Pycnogenol.
  • Results showed that while Pycnogenol exhibited antioxidant properties in vitro, it also caused lens opacity and damage at certain concentrations; however, in vivo, it improved lens conditions in diabetic rats and reduced glycation of proteins.
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Hypericin is the ingredient used to standardize the popular over-the-counter antidepressant medication St. John's Wort. Because hypericin readily produces singlet oxygen and other excited state intermediates, it is a very efficient phototoxic agent in the eye that can potentially induce the development of the cataract photooxidative mechanism.

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The free phenols have been measured in 15 lagers, 6 porters and ales, and 11 light and nonalcoholic beers. Phenols were measured colorimetrically using an oxidation-reduction reaction with Folin-Ciocalteu reagent and catechin as the standard. The order of phenol concentration was ales > lagers > low calorie > nonalcoholic.

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