Electroretinographic assessment of retinal function during acute exposure to normobaric hypoxia.

Background: The current study aimed to investigate retinal function during exposure to normobaric hypoxia.

Methods: Standard Ganzfeld ERG equipment (Diagnosys LLC, Cambridge, UK) using an extended ISCEV protocol was applied to explore intensity-response relationship in dark- and light- adapted conditions in 13 healthy volunteers (mean age 25 ± 3 years). Baseline examinations were performed under atmospheric air conditions at 341 meters above sea level (FIO2 of 21 %), and were compared to hypoxia (FIO2 of 13.