Publications by authors named "Maureen Van de Velde"
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Synopsis of recent research by authors named "Maureen Van de Velde"
- Maureen Van de Velde's research primarily focuses on the role of lymphatic endothelial cells in cancer progression, examining how tumor-exposed lymphatic cells enhance primary tumor growth and contribute to lymphangiogenesis, which is vital for metastatic spread.
- Her work highlights key mechanisms, such as the interaction between uPARAP and VEGFR-2/VEGFR-3 in lymphatic endothelial cells and the establishment of pre-metastatic niches in lymph nodes, providing insights into potential therapeutic targets for inhibiting tumor-associated lymphangiogenesis.
- Van de Velde also emphasizes the importance of reliable in vivo models in studying angiogenesis and lymphangiogenesis, developing innovative methodologies like the ear sponge assay to investigate complex vascular processes in cancer.