Establishing Multiple-Control Responding of Children with Autism to People and Emotions in Context by Utilizing Derived Stimulus Relations.

This study evaluated the efficacy of a set of procedures in evoking responding under multiple stimulus control (identifying emotions when provided a person and context) in a match-to-sample arrangement. Three participants with autism achieved a mastery criterion following direct training of the target relations, and two of the participants additionally demonstrated derived relations without direct training (identifying people when provided an emotion and context). Corrective procedures were effective in promoting the emergence of derived relations for the third participant.

Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan.

Mutations in the human LMNA gene cause a collection of diseases known as laminopathies. These include myocardial diseases that exhibit age-dependent penetrance of dysrhythmias and heart failure. The LMNA gene encodes A-type lamins, intermediate filaments that support nuclear structure and organize the genome.

Is retinopathy of prematurity increasing among infants less than 1250 g birth weight?

Objective: Retinopathy of prematurity (ROP) is a complication seen in many very low birth weight infants. Severe ROP has been called a "marker" for severe disability. The purpose of this study was to evaluate the occurrence and severity of ROP among infants < or =1250 g birth weight treated in the Special Care Nursery at Women & Infants' Hospital over a period of 7 years from 1994 to 2000.