Implementing a Hospital-Acquired Pressure Injury Prevention Bundle in Critical Care.

The emerging field of implementation science (IS) facilitates the sustainment of evidence-based practice in clinical care. This article, the third in a series on applying IS, describes how a nurse-led team at a multisite health system used IS concepts, methods, and tools to implement a hospital-acquired pressure injury (HAPI) prevention bundle on six critical care units, with the aim of decreasing HAPI incidence.

Implementing the Brøset Violence Checklist in the ED.

The emerging field of implementation science (IS) facilitates the sustainment of evidence-based practice in clinical care. This article, the second in a series on applying IS, describes how a nurse-led IS team at a multisite health system implemented the Brøset Violence Checklist-a validated, evidence-based tool to predict a patient's potential to become violent-in the system's adult EDs, with the aim of decreasing the rate of violence against staff. The authors discuss how they leveraged IS concepts, methods, and tools to achieve this goal.

A Nurse-Led Implementation Science Specialist Program.

A well-known challenge in health care is integrating evidence into practice. Implementation science (IS) is a growing field that promotes the sustainable application of evidence-based practice (EBP) to clinical care. Health care organizations have an opportunity to support sustainable change by creating robust IS infrastructures that engage nurses in the clinical environment.

Ethical Challenges in the Care of the Trauma Patient.

A patient with trauma presents a unique and/or complex challenge to the ethical foundation that guides nursing care. Patients with trauma, by the very nature of the suddenness of their injury, are unable to predetermine or express their wishes in the event of a catastrophic injury. The providers who care for patients with trauma do not have an established patient relationship to aid them in decision-making based on what they think the patient would wish or based on past conversations.

Visual intelligence education using an art-based intervention: Outcomes evaluation with nursing graduate students.

Background: Purposeful visual training is effective. Increasingly, visual arts learning interventions are used by multiple disciplines to improve observation and communication skills, critical skills in healthcare.

Purpose: The primary aim was to evaluate enhancement of skills in the observation, perception and communication domains of visual literacy following a fine arts intervention with nursing graduate students.

Universal Design for Learning: A Framework for Blended Learning in Nursing Education.

Background: Blended learning (BL), the combining of face-to-face and online learning, is gaining prominence in nursing education in response to advances in evidence-based learning using technology, the diverse and evolving needs of nursing learners, and unpredictable events impacting nursing education.

Problem: Blended learning requires nursing learners and educators to adapt to new modalities and educators to re-envision learning environments. However, BL lacks an educational framework to guide implementation and is not well explored in the nursing literature.

Use of Evidence-based Practice Models and Research Findings in Magnet-Designated Hospitals Across the United States: National Survey Results.

Background: All nurses have responsibilities to enculturate evidence-based practice (EBP) and translate and implement research findings into nursing care, practices, and procedures.

Aims: To report EBP-related findings from the national Hospital-Based Nursing Research Characteristics, Care Delivery Outcomes, and Economic Impact Survey questionnaire.

Methods: In this cross-sectional survey research study of 181 nursing research leaders, 127 responded to these questions: "Has your hospital adopted or does it use a model of evidence-based practice?" "If yes, what is the name of the model and how is it used?" "Does your hospital implement (translate) findings from nursing research into clinical practice?" "Describe how your hospital implements these findings and whose responsibility it is.

Third Consensus Development Conference on the Safety of Intravenous Drug Delivery Systems-2018.

Purpose: The Third Consensus Conference on the Safety of Intravenous Drug Delivery Systems was convened to evaluate the benefits and risks of available systems and assess ongoing threats to the safety of intravenous drug delivery.

Summary: The Third Consensus Conference on the Safety of Intravenous Drug Delivery Systems convened in Chicago, Illinois in November 2018. An expert panel of healthcare providers with experience in medication quality and safety, pharmacy and nursing operations, information technology, and/or sterile compounding led the conference.

Mentoring students engaging in scholarly projects and dissertations in doctoral nursing programs.

Background: Doctor of Nursing Practice (DNP) programs in the US have grown exponentially, outnumbering Doctor of Philosophy (PhD) in Nursing programs. Faculty are mentoring increasing numbers of students on DNP projects or PhD dissertations.

Purpose: This descriptive study explored faculty characteristics and examined support, engagement, and outcomes of American Association of Colleges of Nursing member nursing faculty mentoring student DNP projects or PhD dissertations.

Discovery and Development of Metal-Catalyzed Coupling Reactions in the Synthesis of Dasabuvir, an HCV-Polymerase Inhibitor.

Dasabuvir (1) is an HCV polymerase inhibitor which has been developed as a part of a three-component direct-acting antiviral combination therapy. During the course of the development of the synthetic route, two novel coupling reactions were developed. First, the copper-catalyzed coupling of uracil with aryl iodides, employing picolinamide 16 as the ligand, was discovered.

Implementing Universal Design Instruction in Doctor of Nursing Practice Education.

Background: Faculty in Doctor of Nursing Practice (DNP) programs identify challenges of increased enrollment and variances in previous student educational preparation and professional experiences that require innovative approaches to curriculum transformation.

Purpose: This article informs nurse educators about the vibrant and inclusive approach of universal design for instruction (UDI), a framework to conceptualize and implement learning strategies in the DNP curriculum.

Approach: UDI is guided by 9 instructional principles that anticipate diverse learners and is intentionally inclusive of multiple ways of learning.

Visual intelligence education as an innovative interdisciplinary approach for advancing communication and collaboration skills in nursing practice.

Background: Recognizing the relationship of keen observation to communication, critical thinking, and leadership in evidence-based literature, educators have expanded the use of art museums to augment visual intelligence skills. The purpose of this pilot intervention was to evaluate an innovative, interdisciplinary approach for integrating visual intelligence skills into an advanced communications and collaboration course.

Method: Collaborating with museum educators, the intervention for doctoral students was conducted at the National Gallery of Art.

National Study of Nursing Research Characteristics at Magnet®-Designated Hospitals.

Objective: To describe the research infrastructure, culture, and characteristics of building a nursing research program in Magnet®-designated hospitals.

Background: Magnet recognition requires hospitals to conduct research and implement evidence-based practice (EBP). Yet, the essential characteristics of productive nursing research programs are not well described.

The Strengths and Challenges of Implementing EBP in Healthcare Systems.

Background: Multihospital healthcare system leaders and individual nurses are challenged to integrate standardized evidence-based practices that support continuous performance improvement in their systems.

Aim: This study was undertaken to evaluate the strength of and the opportunities for implementing evidence-based nursing practice across a diverse 9-hospital system located in the mid-Atlantic region.

Methods: A cross-sectional survey of 6,800 registered nurses (RNs), with a 24% response rate, was conducted to learn about their attitudes, beliefs, and perceptions toward organizational readiness and implementation of EBP.

Staging and defining characteristics of pressure ulcers using photographs by staff nurses in acute care settings.

Purpose: The aim of this study was to determine if a digital photograph obtained by a staff nurse in the acute care setting could be used to determine staging and wound characteristics of a pressure ulcer when viewed by a panel of wound experts as compared to a bedside assessment by a wound expert.

Subjects And Setting: One hundred digital photographs of pressure ulcers were obtained from 69 patients on general and critical care medical-surgical nursing units from 2 Magnet-designated hospitals belonging to a large Mid-Atlantic health care system. Four certified wound ostomy nurses (CWONs), 2 at each hospital site, identified patients with a pressure ulcer for bedside assessment and digital photography.

National survey of hospital nursing research, part 1: research requirements and outcomes.

Objective: The aim of this study was to describe program requirements and scholarly outcomes for registered nurse (RN)-led research in US hospitals.

Background: Magnet recognition emphasis on evidence-based practice and research has stimulated the growth of hospital-based nursing research programs. Hospital policies stipulating whether RNs can lead studies as principal investigators (PIs) varied among members of a regional nursing research consortium.

National survey of hospital nursing research, part 2: facilitators and hindrances.

Objective: The aim of this study was to describe the facilitators and hindrances associated with the conduct of registered nurse-led research in US hospitals.

Background: Hospital-based nursing research programs are growing in response to increasing emphasis on evidence-based practice. Concerns existed about institutional regulations prohibiting staff nurses' ability to be principal investigators of their research studies.

Use of cardiac troponin T in diagnosis and prognosis of cardiac events in patients on chronic haemodialysis.

Background: Patients undergoing chronic haemodialysis frequently have elevated serum cardiac troponin T (cTnT) levels resulting in difficulty in diagnosing acute coronary syndromes (ACS) in these patients. We sought to determine whether: (i) cTnT concentrations were consistent over time; (ii) intradialytic changes in cTnT levels were due to haemoconcentration; (iii) baseline cTnT levels predicted subsequent mortality or ACS.

Methods: We measured serial pre- and post-dialysis cTnT concentrations in 75 asymptomatic patients undergoing chronic haemodialysis at baseline, and at 48 h, 8 months and 15 months.

Writing Across the Curriculum: using Healthy People 2010 and the DHHS Secretary's Award for Innovations in Health Promotion and Disease Prevention.

The authors detail a Writing Across the Curriculum (WAC) exercise that combines the Department of Health and Human Services' Secretary's Award for Innovations in Health Promotion and Disease Prevention (Secretary's Award) and the DHHS document Healthy People 2010. The authors discuss the writing competition as a way to encourage innovative problem solving and provide curricular instructions for using Healthy People 2010 and the Secretary's Award as a WAC exercise.

Learning pain assessment and management: a goal of the End-of-Life Nursing Education Consortium.

Background: Relief of pain for patients requires that palliative care practitioners have knowledge and skill in both pain assessment and the use of pharmacologic and complementary therapies.

Method: Pain assessment and management and the teaching strategies suggested within the End-of-Life Nursing Education Consortium curriculum are presented.

Results: By addressing the pain experienced by patients with life-limiting illnesses and those at the end of life, the quality of care can be greatly improved.

Teaching cultural considerations at the end of life: end of life nursing education consortium program recommendations.

Background: The End of Life Nursing Education Consortium (ELNEC) is an end of life care nursing education program that addresses the many dimensions of culture, including ethnic identity, gender, age, differing abilities, sexual orientation, and religion and spirituality. This article focuses on one of the program's modules entitled "Cultural Considerations in End of Life Care."

Method: The ELNEC "Cultural Considerations in End of Life Care" module, which identifies important cultural considerations as well as strategies and responses to teach cultural competence and sensitivity in undergraduate nursing curriculum, is described.

Achieving quality care at the end of life: a focus of the End-of-Life Nursing Education Consortium (ELNEC) curriculum.

This article introduces the didactic content and teaching strategies presented in the End of Life Nursing Education Consortium (ELNEC) curriculum on the topic of "Achieving Quality Care at the End of Life." The American Association of Colleges of Nursing joined forces with the City of Hope National Medical Center to begin a national education initiative, entitled the, "End of Life Nursing Education Consortium" (ELNEC) (available: http://www.aacn.

Synthesis of an influenza neuraminidase inhibitor intermediate via a highly diastereoselective coupling reaction.

[reaction: see text]. A highly diastereoselective coupling reaction between TBSOP (3) and trityl sulfenimine 4 was developed which provided influenza neuraminidase inhibitor intermediate 7 in 80% yield and >99% de after crystallization. The reaction was shown to be reversible with the high diastereoselectivity resulting from a favorable H-bonding interaction in the major diastereomer.