Long-term survival, nutritional autonomy, and quality of life after intestinal and multivisceral transplantation.

Objective: To assess long-term survival, graft function, and health-related quality of life (QOL) after visceral transplantation.

Background: Despite continual improvement in early survival, the long-term therapeutic efficacy of visceral transplantation has yet to be defined.

Methods: A prospective cross-sectional study was performed on 227 visceral allograft recipients who survived beyond the 5-year milestone.

Nutrition and quality of life following small intestinal transplantation.

Background: The outcome from small bowel transplantation (SBTx) has improved progressively over the past decade raising questions as to whether indications should be broadened from those currently followed based on "TPN (total parenteral nutrition) failure."

Objective And Methods: To assess current outcome, we studied the effect of transplantation on nutritional autonomy, organ function, and quality of life (QoL) measured by a validated self-administered questionnaire containing 26 domains and 130 questions, for a minimum of 12 months in a cohort of 46 consecutively transplanted patients between June 2003 and July 2004. The majority of transplanted patients (76%) had intestinal failure because of extreme short bowel, the remainder having either chronic pseudo-obstruction or porto-mesenteric vein thrombosis (PMVT).