Clin Spine Surg
November 2024
Purpose: Threshold scores for patient acceptable symptom state (PASS) represent the score beyond which a patient considers themselves "well." We aimed to determine PASS thresholds for the symptom severity scale (SSS) and functional status scale (FSS) of the Boston Carpal Tunnel Questionnaire in a sample of patients 1 year following carpal tunnel release.
Methods: Adults (≥ 18 years) from a single, tertiary-care academic institution were contacted 12 ± 1 months after carpal tunnel release.
Purpose: Environmental sustainability is an important issue in health care because of large amounts of greenhouse gases attributable to hospitals. The operating room has been highlighted as one of the highest contributors, prompting several initiatives by organizations focused on the care of hand and upper extremity conditions. This study aimed to quantify and compare the carbon footprint of a common hand surgery in two different surgical settings, the procedure room (PR) and operating room.
View Article and Find Full Text PDFPurpose: Patient-reported outcome measures intend to capture patients' perspectives on their health status. However, the patient-perceived applicability of many of these patient-reported outcome measures is unknown. We hypothesized that patients experiencing greater upper extremity disability and greater pain interference would be more likely to report that the Quick Disabilities of the Arm, Shoulder, and Hand questionnaire (QuickDASH) survey content is responsive to their daily lives and goals in seeking surgical care.
View Article and Find Full Text PDFInt J Environ Res Public Health
August 2021
Self-compassion recognises a meaning of life's suffering, aligning with existential positive psychology. Although this construct is known to protect our mental health, how to augment self-compassion remains to be evaluated. Social work students suffer from high rates of mental health problems; however, research into self-compassion in this population remains to be developed.
View Article and Find Full Text PDFCold Spring Harb Mol Case Stud
November 2016
KBG syndrome is a rare autosomal dominant genetic condition characterized by neurological involvement and distinct facial, hand, and skeletal features. More than 70 cases have been reported; however, it is likely that KBG syndrome is underdiagnosed because of lack of comprehensive characterization of the heterogeneous phenotypic features. We describe the clinical manifestations in a male currently 13 years of age, who exhibited symptoms including epilepsy, severe developmental delay, distinct facial features, and hand anomalies, without a positive genetic diagnosis.
View Article and Find Full Text PDFA fixed-wing aircraft (Beechcraft KingAir B200 C) fitted as an airborne intensive care facility is described. It completed 2000 missions from 1987-1992 for distances up to 1300 km. Features include: 1.
View Article and Find Full Text PDFBlood samples were collected via jugular catheters from ovariectomized rats at 10-minute intervals for one hour before and two hours after microinjection of -.5 microliter of either saline vehicle or morphine sulfate (10 micrograms) into the dorsal raphe nucleus (DRN) or adjacent periaqueductal gray by means of chronically-implanted guide cannulae. LH was measured by radioimmunoassay and mean pre-injection and mean post-injection values were compared for each rat (t test) as well as for each treatment group (paired t test).
View Article and Find Full Text PDFThe aim of this study was to determine whether there is a decrease in fetal cortisol levels associated with the respiratory distress syndrome (RDS). Eighteen newborn infants of less than 37 weeks' gestation who developed moderate to severe forms of RDS did have a significantly lower (P less than 0.02) mean cord plasma cortisol concentration at birth than that observed in 67 unaffected infants of similar gestational age; mean values +/- standard errors were 3.
View Article and Find Full Text PDFAm J Obstet Gynecol
May 1976
Cortisol was determined by a competitive protein-binding method in umbilical cord plasma from pregnancies of 37 or more weeks' gestation. In 162 cases of vaginal delivery following spontaneous labor the mean +/- S.E.
View Article and Find Full Text PDFAmpicillin treatment in the last trimester of pregnancy had no significant effect on the levels of estradiol, estriol, or cortisol in maternal plasma. Urinary estriol excretion was, however, notably decreased during or following ampicillin treatment in six out of 10 patients. These results suggest that the plasma estrogen assays have greater validity than the urinary estriol assay in assessing fetoplacental endocrine function during a period of ampicillin treatment of the mother.
View Article and Find Full Text PDFEstrogen concentrations in maternal plasma were determined in ten apparently normal patients attending clinic in the last trimester of pregnancy before, during, and after a maximum of four weeks isoxsuprine treatment. Eleven control patients were also studied at similar times of pregnancy. Isoxsuprine treatment appeared to have no specific effect on the levels of either estradiol alone or on total estrogens with all patients studied showing some increase in the concentrations of these estrogens as the pregnancies approached term.
View Article and Find Full Text PDFThe purpose of this study was to investigate cortisol levels in the fetal circulation prior to delivery. Fetal scalp plasma cortisol levels during labor were significantly lower than those in maternal peripheral plasma but significantly higher than those in cord plasma at delivery. Cortisol levels in fetal scalp plasma did not correlate significantly with those in either maternal or cord plasma.
View Article and Find Full Text PDFThe average estradiol concentrations in umbilical cord plasma from newborns which developed respiratory distress with or without hyaline membrane disease (RDS) were lower by 25% than in controls. Complication of pregnancy by maternal diabetes or pruritus has been associated with abnormalities in estrogen concentrations in the mother, but cord plasma estradiol levels in these cases were essentially normal. Because of reports that treatment of the mother before delivery with estrogens or glucocorticoids results in a decreased incidence of RDS in newborns the relationship between endogenous estradiol and cortisol levels in cord plasm was investigated.
View Article and Find Full Text PDFEstradiol and hydrocortisone levels in maternal and fetal (umbilical cord) blood in human pregnancy can be simultaneously assessed by this method. Chromatography on microcolumns of Sephadex LH-20 with benzene:methanol (85:15) as developing solvent is used to separate estradiol, hydrocortisone, and isatin (a yellow-colored substance used as marker) from interfering steroids. Human late pregnancy plasma is used as the source of both sex hormone-binding globulin and transcortin for the competitive protein-binding assay of estradiol and hydrocortisone, respectively.
View Article and Find Full Text PDFAm J Obstet Gynecol
June 1972