Publications by authors named "Maudy van der Heiden"
Article Synopsis
- Invasive motor cortex stimulation (iMCS) is explored as a treatment for persistent neuropathic pain, but its mechanisms are still unclear, despite noted changes in brain blood flow.
- A systematic review analyzed various neuroimaging studies, ultimately including six studies that observed significant changes in regional cerebral blood flow (rCBF) when the iMCS device was activated, particularly in areas like the cingulate gyrus and thalamus.
- The results indicated both increased and decreased rCBF in specific brain regions when switching the iMCS "ON" compared to "OFF," suggesting potential pathways for its analgesic effects in pain management.
Experimental treatments for treating neuropathic pain include transcranial magnetic stimulation (TMS) and invasive electric motor cortex stimulation (iMCS) of the primary motor cortex (M1). Mechanisms of action of both methods, however, remain largely elusive. Within this paper, we focus on animal-based experiments in order to investigate the biological mechanisms that are involved in alleviating pain by use of TMS and/or iMCS.
View Article and Find Full Text PDF