Fluorinated Aliphatic Diazirines: Preparation, Characterization, and Model Photolabeling Studies.

The previously unknown difluoromethyl diazirines and the previously neglected trifluoromethyl-aliphatic diazirines were synthesized and characterized. Model photolabeling experiments and biological studies showed that these compounds could indeed be used as photoaffinity labels.

[P elements comprising mini-white marker gene suppression features in intergenic regions of Drosophila melanogaster genome].

12 492 intergenic regions were stratified into four classes according to protein coding genes mutual orientation flanking an intergenic region. It was revealed that transposon insertion sites number linearly correlates with number of promoters (none, one, or two) in an intergenic region. The vast majority oftransposons reside in intergenic regions with two promoters.

Long-path second-harmonic interferometer with nanosecond time resolution: reliable diagnostic tool for electron density measurement in pulsed plasma devices.

We describe the performance of a second-harmonic interferometer (SHI) to measure, on an optical path exceeding 12 m, the electron plasma density of two plasmoids formed in separate theta-pinch chambers and then merged in a central compression chamber after undergoing acceleration and compression. The excellent mechanical stability and a time resolution better than 50 ns suggest the application of SHI, especially in pulsed plasma devices with limited optical accesses.

A metric for the evaluation of dense vector field visualizations.

In this work, we present an intuitive image-quality metric that is derived from the motivation of DVF visualization. It utilizes the features of the resulting image and effectively measures the similarity between the output of the visualization method and the input flow data. We use the angle between the gradient direction and the original vector field as a measure of such similarity and the gradient magnitude as an importance measure.

[Automatization of the monitoring of medical staff--the basis of their continued professional education].

Some reasons preventing realization of a principle of vocational training of the medical personnel of health service BC the Russian Federation, including the expense of insufficient efficiency of planning of formation are considered in the article. Recommendations about working out of the personnel register are given.

[Changes in the blood vessels of the lungs under physical loads at high altitude].

Changes of the pulmonary artery branches in rats at the state of relative physiological rest undergo two stages during the process of individual adaptation for 60 days. The first is characterized with generalized decrease of the lumen and with thickening of the vascular wall as a result of reflectory spasm and edematous swelling of the arteries, the second--with a relative dilatation of the lumen and with decreasing thickness of the vascular wall, as a result of decreasing reflectory spasm and edematous phenomena. The physical load increases the organism's elevated oxygen consumption under conditions of high-altitude, which is increased by itself; this intensifies the function of the pulmonary blood bed.

[Hypotensive activity of the plasma proteins in a normovolemic blood exchange transfusion].

The effect of post-hemotransfusion protein fractions on blood pressure, microcirculation and physiologically active substances has been studied in stimulated blood replacement by homologous animal blood. The in vivo and in vitro experiments have revealed that subfraction of hemotransfusion plasma macromolecular proteins has a prominent antihypertensive effect, leading to blood flow slowing in the microvascular bed. Hemotransfusion plasma proteins possess high serotonin-releasing activity.

[Anterior epidurography with verographin].

Direct contrasting of the anterior epidural space with 9-10% verografin solution was conducted in 123 patients (120 with discogenic radiculitis, 2 with tumors, and 1 with injury to the spine). The epidural space was contrasted for a distance of 3-4 intervertebral spaces and no stimulation of the epidural structures occurred. The epidurograms demonstrated convincing information concerning the character of the protrusion and prolapse of the intervertebral discs and the existence of block of the epidural space in tumors.

[Rheological properties of solutions of purified hemoglobin and blood].

The results of studying rheological properties of solutions of purified hemoglobin and its mixtures with blood indicate low relative viscosity of the solutions, as well as an appreciable decrease, when the blood is diluted with these solutions, of the indicators of its viscosity and yield stress without impairment of the blood suspension stability. This allows the conclusion about prospectiveness of further studies aimed at the design of hemocorrectors on the basis of extraerythrocytic hemoglobin.