Composition and Biological Activity of Flavonoid-containing Fractions of an Extract from Gratiola officinalis L.

Introduction: Gratiola officinalis L. (hedge hyssop), a medicinal plant of the Scrophulariaceae family, has diuretic, purgative, and vermifuge properties. It is used as a herbal tea to treat chronic gastroenteritis, renal colic, jaundice, and intestinal worms.

Use of cells in quercetin detection.

The possibility of detection and determination of flavonoids by using microbial cells was shown for the first time using the quercetin - Sp245 model system. The activity of the flavonoids quercetin, rutin and naringenin toward Sp245 was evaluated. It was found that when the quercetin concentration ranged from 50 to 100 μM, the number of bacterial cells decreased.