Publications by authors named "Mattila Marja-Leena"

This study aimed to evaluate the effect of linguistic complexity and individual background variables (i.e. linguistic and cognitive abilities, degree of autistic traits, and sex) on speech disfluencies in autistic young adults and controls.

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Purpose: The aim of this study was to investigate several possible factor structures of the Autism Spectrum Screening Questionnaire (ASSQ).

Materials And Methods: We used the 27-item screening tool for school-aged children in a general population of 8-year-old children ( = 3,538) and compared the occurring solutions to previously published factor models.

Results: A one-factor solution and a four-factor solution were identified in Exploratory Factor Analysis (EFA) and confirmed with Confirmatory Factor Analysis (CFA), while two-, three-, five- and six-factor solutions were rejected.

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Purpose: The purpose of this study was to examine the nature of speech disfluencies in autistic young adults and controls by using a wide-range disfluency classification of typical disfluencies (TD; i.e., filled pauses, revisions, abandoned utterances, and multisyllable word and phrase repetitions), stuttering-like disfluencies (SLD; i.

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Background: Despite increasing knowledge of social communication skills of autistic peole, the interrelatedness of different skills such as non-linguistic comprehension, social inference and empathizing skills is not much known about. A better understanding of the complex interplay between different domains of social communication helps us to develop assessment protocols for individuals with social communication difficulties.

Aims: To compare the performances of autistic young adults, young adults with autistic traits identified in childhood and control young adults in social communication tasks measuring non-linguistic comprehension, social inference and empathizing skills.

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Previous social-pragmatic and narrative research involving autistic individuals has mostly focused on children. Little is known about how autistic adults and adults who have autistic traits but do not have a diagnosis of an autism spectrum disorder (ASD) interpret complex social situations and tell narratives about these situations. We asked 32 autistic young adults, 18 adults with autistic traits but no ASD diagnosis, and 34 non-autistic young adults to watch socially complex situations and freely tell narratives about what they thought was occurring in each situation.

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Importance: Although topical antibiotics are often prescribed for treating acute infective conjunctivitis in children, their efficacy is uncertain.

Objective: To assess the efficacy of topical antibiotic therapy for acute infective conjunctivitis.

Design, Setting, And Participants: A randomized clinical trial was conducted in primary health care in Oulu, Finland, from October 15, 2014, to February 7, 2020.

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Article Synopsis
  • There is an increased focus on analyzing how brain networks behave over time in resting state fMRI studies, particularly comparing individuals with autism to typically developing controls.
  • The research employed hierarchical clustering to categorize brain image volumes from adolescents with Autism Spectrum Disorder (ASD) and typically developing controls, revealing significant differences in voxel-wise means across various resting state networks (RSNs).
  • Findings indicated that while brain state proportions were similar, the ASD group demonstrated more varied activation patterns and reduced deactivation across multiple networks, highlighting differences in brain connectivity and activity states between the two groups.
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  • This study focused on comparing autistic young adults to neurotypical young adults regarding social interactions and physiological responses.
  • Results showed significant differences in how each group interpreted social cues, paid attention to faces, and reacted physiologically (especially in terms of heart rate variability).
  • A notable finding was that autistic young adults who paid more attention to facial emotions tended to interpret social situations better, indicating that higher social attention helps with social understanding and emotional regulation.
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Objective: The staircase (Sc) pattern enamel microstructure is an expression of an impaired ameloblast function. It has been reported to appear in the neonatal line (NNL), the accentuated stria evincing live birth in deciduous tooth enamel. Our objective was to investigate the prevalence of Sc NNL in deciduous tooth types and its possible association with perinatal circumstances.

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Background: There is a lack of studies about how adolescents experience the interaction during dental visits. The experienced interaction during dental visits will influence how adolescents take care of their oro-dental health, and how they attend at the dentist's office.

Aim: To explore the interaction experiences during dental visits of 18-year-olds with or without a history of caries.

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The aim of the current study was to investigate subtle characteristics of social perception and interpretation in high-functioning individuals with autism spectrum disorders (ASDs), and to study the relation between watching and interpreting. As a novelty, we used an approach that combined moment-by-moment eye tracking and verbal assessment. Sixteen young adults with ASD and 16 neurotypical control participants watched a video depicting a complex communication situation while their eye movements were tracked.

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  • This study aimed to explore the link between oral health knowledge, attitudes, and habits and how they relate to perceived oral symptoms in 12-year-olds, noting the differences between boys and girls.
  • The research involved 588 children from 15 schools in Turku, Finland, using various statistical methods to assess these relationships.
  • Results showed that while healthy habits were linked to fewer symptoms, girls exhibited better health practices but reported more gingival bleeding compared to boys, with no significant gender differences in knowledge or the impact of habits on symptoms.
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Background: Previous studies investigating neuropsychological functioning of children with autism spectrum disorder (ASD) have only analysed certain abilities, such as executive functions or language. While comprehensive assessment of the neuropsychological profile of children with ASD has been the focus of recent research, most of the published evidence originates from single centres. Though studies on differences in neuropsychological features of children with ASD across countries are essential for identifying different phenotypes of ASD, such studies have not been conducted.

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  • The study compared changes in parents' oral health behaviors, knowledge, and attitudes during a 3.4-year intervention in two Finnish towns: Pori (where the program was implemented) and Rauma (a reference area).
  • In the initial phase (2001-2003), parents in Pori showed improvement in behaviors, especially mothers who recognized the importance of brushing for health and appearance.
  • By the later phase (2003-2005), behavior changes in both towns were similar, likely due to the spread of the intervention's influence through local media, indicating that promoting children's oral health can also benefit their parents' habits.
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The present study examined attention and memory load-dependent differences in the brain activation and deactivation patterns between adolescents with autism spectrum disorders (ASDs) and typically developing (TD) controls using functional magnetic resonance imaging. Attentional (0-back) and working memory (WM; 2-back) processing and load differences (0 vs. 2-back) were analysed.

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The main purpose of this study was to explore whether subjective perception of interaction with dental staff is associated with dental fear in a population-based sample of 18-yr-old adolescents (n = 773). The interaction was measured using the Patient Dental Staff Interaction Questionnaire (PDSIQ), validated with exploratory and confirmatory factor analyses, which yielded the factors of 'kind atmosphere and mutual communication', 'roughness', 'insecurity', 'trust and safety', and 'shame and guilt'. Dental fear was measured using the Modified Dental Anxiety Scale (MDAS).

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In resting state functional magnetic resonance imaging (fMRI) studies of autism spectrum disorders (ASDs) decreased frontal-posterior functional connectivity is a persistent finding. However, the picture of the default mode network (DMN) hypoconnectivity remains incomplete. In addition, the functional connectivity analyses have been shown to be susceptible even to subtle motion.

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Article Synopsis
  • The study investigated the link between oral health behaviors in pre-teens and their educational plans in later adolescence, factoring in gender and parents' jobs.
  • Data was collected from over 1,400 fifth and sixth graders in Pori, Finland, who reported their toothbrushing habits and consumption of various food and drink items.
  • Results indicated that good oral health habits significantly influenced educational aspirations, suggesting that health behaviors develop early and can impact future opportunities, regardless of parental occupation.
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The aim was to investigate whether dental fear was associated with the sense of coherence (SOC) among 18-yr-old adolescents (n = 777). Cross-sectional data from a prospective cohort of a random sample of families from Finland and their first-born children were used. Dental fear was measured using the Modified Dental Anxiety Scale and categorized as high dental fear for scores of 19-25 and as no to moderate dental fear for scores of 5-18.

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Childhood autism, Asperger's syndrome and atypical autism together make up autism spectrum disorders (ASDs) with a prevalence of 0.6-0.7%.

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Article Synopsis
  • A study compared social anxiety symptoms in parents of children with autism spectrum disorders (ASDs) to parents in the community using the Social Phobia and Anxiety Inventory (SPAI).
  • Results showed that mothers of children with ASDs experienced significantly higher rates of social anxiety (15.6%) compared to community mothers (6.7%), while the difference in social anxiety symptoms was not as pronounced for fathers.
  • The findings indicate a need for support for parents of children with ASDs, as their social anxiety could impact their children's emotional development and overall family well-being.
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Article Synopsis
  • The Finnish Autism Spectrum Screening Questionnaire (ASSQ) was assessed for validity and cut-off scores using a sample of 4,408 8-year-old children rated by parents and teachers.
  • A subgroup of 104 children underwent thorough evaluation, including structured interviews and observations, to ensure accurate ASD diagnoses based on DSM-IV-TR criteria.
  • For Finnish higher-functioning children aged 7 to 12, optimal ASSQ cut-off scores were identified as 30 for clinical settings and 28 for general population screening, highlighting the importance of tailored screening across different languages and cultures.
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Background: Diffusion tensor imaging (DTI) enables measurements and visualization of the microstructure of neural fiber tracts. The existing literature on autism spectrum disorders (ASDs) and DTI is heterogenous both regarding methodology and results.

Purpose: To compare brain white matter of high-functioning individuals with ASDs and controls.

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FMRI was performed with the dynamic facial expressions fear and happiness. This was done to detect differences in valence processing between 25 subjects with autism spectrum disorders (ASDs) and 27 typically developing controls. Valence scaling was abnormal in ASDs.

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Objective: The latest definitions of autism spectrum disorders (ASDs) were specified in DSM-IV-TR in 2000. DSM-5 criteria are planned for 2013. Here, we estimated the prevalence of ASDs and autism according to DSM-IV-TR, clarified confusion concerning diagnostic criteria, and evaluated DSM-5 draft criteria for ASD posted by the American Psychiatry Association (APA) in February 2010.

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