Publications by authors named "Mattias C U Gustafsson"
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Synopsis of recent research by authors named "Mattias C U Gustafsson"
- Recent research by Mattias C U Gustafsson predominantly focuses on the interactions between Streptococcus pyogenes and human immune responses, particularly the immunogenicity and sequence variability of the M protein, which helps the pathogen evade host immunity through weak antibody responses and antigenic variation.
- Another significant area of his work investigates the role of human complement factor H (FH) in relation to streptococcal M proteins, demonstrating how specific protein interactions do not promote phagocytosis resistance or virulence, challenging earlier assumptions in pathogen-pathogen interactions.
- Additionally, Gustafsson's research extends to the functional dynamics of peroxisome proliferator-activated receptor (PPAR) subtypes in various biological contexts, including their implications in placental development, skin diseases like psoriasis, and cancer cell proliferation, highlighting the complex regulatory roles these receptors play in both normal and pathological conditions.
