Publications by authors named "Mattia Pirani"
A digitally supported multimodal lifestyle program to promote brain health among older adults (the LETHE randomized controlled feasibility trial): study design, progress, and first results.
Anna Rosenberg Helena Untersteiner Anna Giulia Guazzarini Markus Bödenler Jeroen Bruinsma Mattia Pirani
Alzheimers Res Ther
November 2024
Background: The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multimodal lifestyle intervention yielded cognitive and other health benefits in older adults at risk of cognitive decline. The two-year multinational randomized controlled LETHE trial evaluates the feasibility of a digitally supported, adapted FINGER intervention among at-risk older adults. Technology is used to complement in-person activities, streamline the intervention delivery, personalize recommendations, and collect digital biomarkers.
View Article and Find Full Text PDFLETHE: A Digital Intervention for Cognitive Decline.
Vasileios S Loukas Thomas Kassiotis Ignacio Lamata Martinez Lefteris Koumakis Jeroen Bruinsma Mattia Pirani
Annu Int Conf IEEE Eng Med Biol Soc
July 2023
Article Synopsis
- - Dementia primarily affects elderly populations, with risk factors including pathological, lifestyle, and heritable influences; early diagnosis and management are crucial since there is currently no cure.
- - The LETHE project focuses on preventing cognitive decline in at-risk elderly individuals using a Big Data platform for personalized risk detection and intervention, aiming to evaluate its effectiveness through a 2-year clinical trial.
- - LETHE introduces a comprehensive approach to health management by leveraging advanced patient monitoring systems to enhance outcomes, predict cognitive decline, and support adherence to lifestyle interventions.