Publications by authors named "Mattia Basile"

Background: Patients experiencing non-ST segment elevation acute-coronary-syndromes (NSTE-ACS) often present with multivessel-coronary-artery-disease (MVD). An immediate complete multivessel revascularization (MVR) - within the index hospitalization - may be considered the default therapeutic strategy, although its risk-to-benefit profile has not been definitively established through dedicated clinical trials.

Methods: A systematic review and meta-analysis, adhering to MOOSE and PRISMA guidelines, was conducted to assess studies comparing immediate MVR versus a conservative culprit-only revascularization (COR) in NSTE-ACS with MVD.

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Article Synopsis
  • The study looked at how to identify problems in patients with certain heart issues using a test called acetylcholine (ACh) provocation testing.
  • Researchers created a score called the ABCD score to help predict if patients would have a positive test result based on specific factors.
  • The ABCD score could help reduce unnecessary testing for patients with high scores, making treatments safer and more efficient, but more research is needed to confirm its effectiveness.
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  • Myocardial injury is common in COVID-19 patients, but the impact of COVID-19 vaccines on this risk is not well understood.
  • A study involving 1019 hospitalized COVID-19 patients found that older age, chronic kidney disease, and hypertension were linked to myocardial injury, while vaccination status did not significantly impact risk.
  • In patients aged 76 and older, vaccines appeared to protect against myocardial injury, but in those aged 60 and younger, vaccination was associated with an increased risk of injury.
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Background And Aims: Air pollution is emerging as an important risk factor for acute coronary syndrome (ACS). In this study, we investigated the association between short-term air pollution exposure and mechanisms of coronary plaque instability evaluated by optical coherence tomography (OCT) imaging in ACS patients.

Methods: Patients with ACS undergoing OCT imaging were retrospectively selected.

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Air pollution, noise pollution, and light pollution have emerged as important but often overlooked risk factors for cardiovascular disease. In this review, we examine the emerging concept of the exposome, highlighting the close relationship between environmental exposure (e.g.

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Background: Cardiovascular sequelae after COVID-19 are frequent. However, the predictors for their occurrence are still unknown. In this study, we aimed to assess whether myocardial injury during COVID-19 hospitalization is associated to CV sequelae and death after hospital discharge.

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Background: Coronary vasomotor abnormalities are important causes of myocardial ischemia in patients with nonobstructive coronary artery disease (NOCAD). However, the role of air pollution in determining coronary vasomotor disorders has never been investigated.

Objectives: We aimed to evaluate the association between long-term exposure to particulate matter 2.

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