Synthetic mesh versus biological mesh to prevent incisional hernia after loop-ileostomy closure: a randomized feasibility trial.

Background: Incisional hernia is a frequent complication after loop-ileostomy closure, rationalizing hernia prevention. Biological meshes have been widely used in contaminated surgical sites instead of synthetic meshes in fear of mesh related complications. However, previous studies on meshes does not support this practice.

Prospective, Randomized Study on the Use of Prosthetic Mesh to Prevent a Parastomal Hernia in a Permanent Colostomy: Results of a Long-term Follow-up.

Background: Parastomal hernias are common with permanent colostomies and prone to complications. The short-term results of trials of parastomal hernia prevention are widely published, but long-term results are scarce.

Objective: The aim of the study is to detect the long-term effects and safety of preventive intra-abdominal parastomal mesh.

Quality of life and pelvic floor dysfunction symptoms after hysterectomy with or without pelvic organ prolapse.

Objective: To assess the effect of hysterectomy with or without pelvic organ prolapse (POP) on health-related quality of life (HRQoL) and pelvic floor disorders.

Study Design: Prospective clinical study at two central hospitals in Finland. During one year 322 women underwent elective hysterectomy for benign conditions with or without vaginal wall repair.

[Functional obstructed defecation syndrome].

The complex neural coordination and physiology of normal defecation has not yet been completely explained. A defecation event can be disturbed for many reasons, the most common being associated with pregnancy and childbirth, gynaecological descent or neurogenic disturbances of the brain-bowel axis. Causes of obstructed defecation are elucidated by functional imaging and functional investigations of the pelvic floor.

[Dysfunctions associated with pelvic floor function, and their diagnostics].

Pelvic floor dysfunctions are common, mainly female ailments that are usually benign but decreasing the quality of life. Their main risk factors include pregnancy, childbirth and ageing. Investigation and treatment of pelvic floor dysfunctions should be carried out in a pervasive manner, including observation of all compartments, structures and functions of the pelvic floor.

Development of colorectal tumors in colonoscopic surveillance in Lynch syndrome.

Background & Aims: Mutation carriers in Lynch syndrome families have a high risk for developing colorectal cancer during their lifetime. This study was designed to assess the cumulative risk for the development of colorectal adenoma or carcinoma in prospective colonoscopic surveillance.

Methods: Data from the Finnish Hereditary Colorectal Cancer Registry electronic database on 420 Lynch syndrome mutation carriers without previous colorectal tumors were reviewed.

The role of mediolateral episiotomy during labour: analysis of risk factors for obstetric anal sphincter tears.

Background: To determine risk factors for third-degree and complete third- or fourth-degree anal sphincter tears in vaginal delivery.

Methods: This is a retrospective comparative study. Fifty-three women who had sustained an anal sphincter tear were compared with 9,178 women without such a complication between August 1997 and October 2001.

Immediate repair of obstetric anal sphincter rupture: medium-term outcome of the overlap technique.

Purpose: Overlap sphincteroplasty is gaining popularity in the primary repair of obstetric sphincter ruptures. This study was designed to evaluate the medium-term outcome of the overlap technique.

Methods: Between August 1997 and October 2001, 31 consecutive females who were diagnosed with a complete third-degree or fourth-degree anal sphincter rupture underwent overlap sphincteroplasty immediately after delivery.

Open vs. laparoscopic surgery for rectal prolapse: a case-controlled study assessing short-term outcome.

Purpose: This study was undertaken to evaluate the efficacy and safety of laparoscopic repair for rectal prolapse.

Methods: A case-control study was undertaken. The case group consisted of a consecutive series of patients who underwent laparoscopic repair for rectal prolapse between February 1993 and June 2000.