Publications by authors named "Matthijs Oosterbeek"

Sedentary endoparasites such as cyst and root-knot nematodes infect many important food crops and are major agro-economical pests worldwide. These plant-parasitic nematodes exploit endogenous molecular and physiological pathways in the roots of their host to establish unique feeding structures. These structures function as highly active transfer cells and metabolic sinks and are essential for the parasites' growth and reproduction.

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Article Synopsis
  • Retrotransposons significantly influence the evolution of host genomes, with historical DNA sequence studies illustrating their past activities but lacking insights into current transposition capabilities.
  • A new method called ALE-seq has been developed to better identify active retrotransposons in large and complex genomes like those of crops, allowing for the detection of extrachromosomal linear DNA (eclDNA).
  • Using ALE-seq, researchers found a heat-stress-activated Copia family retrotransposon in rice and identified a developmentally regulated Gypsy family retrotransposon in tomatoes, while also creating a bioinformatics pipeline for analyzing retroelement activity without relying on high-quality genomic references.
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