Publications by authors named "Matthieu Saada"
Article Synopsis
- * This study analyzed cases of C bantiana infections in France and its territories, involving patients who were diagnosed through a comprehensive surveillance program, focusing on survival rates and the presence of central nervous system (CNS) involvement.
- * Out of 23 patients identified from 2002 to 2022, 65% had CNS involvement, with a notable increase in cases reported in 2022, indicating a possible correlation with environmental factors like rising temperatures.
Eosinopenia <100/μL as a marker of active COVID-19: An observational prospective study.
J Microbiol Immunol Infect
February 2021
Objectives: To analyse the diagnostic performance of eosinopenia, alone or combined with polymorphonuclear neutrophils (PMN) and/or lymphocytes, as a marker of active COVID-19 in patients hospitalized for suspicion of SARS-CoV-2 infection.
Methods: A prospective observational study including patients hospitalized for suspicion of COVID-19 in a COVID unit was performed from 20th March to 5th April 2020, in Perpignan, France. Patients for which there was a doubt upon diagnosis, who were recently under oral corticosteroids, had myeloid malignancy or human immunodeficient virus infection were excluded.
Article Synopsis
- The study aimed to assess how the timing of diagnosis impacts the characteristics and outcomes of infective endocarditis (IE), comparing cases diagnosed within one month of first symptoms to those diagnosed later.
- Of the 486 IE cases analyzed, 25% were diagnosed late; early diagnosis was linked to female patients, prosthetic valves, and specific pathogens like staphylococci.
- The findings indicated that while in-hospital mortality was higher in early-diagnosed cases, late diagnosis allowed for more valve surgeries and better overall prognosis.
Objective: We explored the impact of lifelong cumulative HIV viremia on immunological recovery during antiretroviral therapy, according to the timing of treatment initiation.
Methods: We estimated lifelong cumulative HIV viremia in patients followed in the ANRS PRIMO cohort since primary infection, including 244 patients who started treatment during PHI and had at least one treatment interruption, and 218 patients who started treatment later but with no interruptions. The impact of cumulative viremia on current immunological status was analysed using linear and logistic regression models.