Publications by authors named "Matthias Schaupp"
Objectives: To examine the perceptions of family members of patients with disorders of consciousness (DOC) in regard to the patients' level of consciousness, communicative status, and prognosis as compared with the objective medical categories, and to elicit the family members' self-reported practice of treatment decision-making.
Design: Cross-sectional semiquantitative survey.
Setting: Five specialized neurologic rehabilitation facilities.
Article Synopsis
- The KOPF-R registry aims to study long-term outcomes for patients with severe disorders of consciousness undergoing acute rehabilitation, focusing on factors that affect recovery.
- It is a multicenter study set in five specialized rehabilitation facilities in Bavaria, Germany, enrolling patients with disorders like vegetative state or minimally conscious state over an ongoing period.
- Key outcomes measured include patient progress using the Coma Recovery Scale-Revised (CRS-R) and Functional Independence Measure (FIM), along with various clinical, sociodemographic, and therapeutic data.
The human oncogene bcl-2 exerts protective functions in numerous models of apoptotic cell death and increased oxidative stress. We investigated the effects of inducible bcl-2 overexpression on cellular survival and redox status in dopaminergic rat pheochromocytoma PC 12 cells. Induction of high-level expression of bcl-2 in PC 12 cells resulted in generation of oxidative stress and cessation of growth by cell cycle arrest.
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