Publications by authors named "Matthias Paland"

Article Synopsis
  • - The ADRISK trial is a study focused on patients with locally advanced head and neck squamous cell carcinoma (HNSCC) who are at high risk of recurrence after surgery.
  • - It compares the effectiveness of standard adjuvant radio(chemo)therapy (aRCT) with cisplatin to aRCT combined with pembrolizumab, an immunotherapy drug, in improving event-free survival.
  • - The trial involves 240 patients with specific criteria and aims to assess outcomes in terms of event-free and overall survival, with recruitment commencing in August 2018 and still ongoing.
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Treatment of cancer patients has become challenging when large parts of hospital services need to be shut down as a consequence of a local COVID-19 outbreak that requires rapid containment measures, in conjunction with the shifting of priorities to vital services. Reports providing conceptual frameworks and first experiences on how to maintain a clinical hematology/oncology service during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are scarce. Here, we report our first 8 weeks of experience after implementing a procedural plan at a hematology/oncology unit with its associated cancer center at a large academic teaching hospital in Germany.

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Background: International travel contributes to the spread of multidrug-resistant microorganisms including extended spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE). We assessed the proportion of faecal carriers of ESBL-PE among 211 patients with gastrointestinal symptoms who returned to Berlin, Germany, after international travel.

Methods: ESBL-PE were screened for on chromogenic agar, antimicrobial susceptibility testing was performed, and ESBL-genes were genotyped.

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