Publications by authors named "Matthias Olbrich"
1. The metabolism of dydrogesterone was investigated in human liver cytosol (HLC) and human liver microsomes (HLM). Enzymes involved in dydrogesterone metabolism were identified and their relative contributions were estimated.
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- Simvastatin and fenofibrate are commonly used together to treat dyslipidemia, but potential drug interactions have raised concerns about their simultaneous use.
- A study involving 85 healthy participants examined the effects of taking simvastatin either alone, together with fenofibrate at the same time, or at staggered intervals.
- Results showed minimal changes in the pharmacokinetics of simvastatin, suggesting that the interaction between these drugs is not clinically significant and allowing for their safe combined use, regardless of timing.