Synthesis, structural assignments and antiinfective activities of 3--benzyl-carvotacetone and 3-hydroxy-2-isopropyl-5-methyl--benzoquinone.

In an attempt to synthesize carvotacetone analogues, new 3--benzyl-carvotacetone ( and previously reported 3-hydroxy-2-isopropyl-5-methyl--benzoquinone () were synthesized from piperitone (). In this work, we describe the synthesis of and other analogues from . Luche reduction of to -piperitol (, followed by benzylation yielded 3--benzyl-piperitol ().