UAVs are widely used for aerial reconnaissance with imaging sensors. For this, a high detection performance (accuracy of object detection) is desired in order to increase mission success. However, different environmental conditions (negatively) affect sensory data acquisition and automated object detection.
View Article and Find Full Text PDFThis paper develops a novel optimization methodology for designing Shape-memory-alloy resisting devices (SMARDs) and optimally allocating them to inelastic multistory structures. The solution algorithm is a control gains optimization procedure that refers to a formal optimization problem with an objective function subject to the state-space equation and design limitations. The objective function integrates the squared state components in time, and the state-space equation consists of a newly introduced state vector form that reflects the system's inelasticity.
View Article and Find Full Text PDFProtein-ligand interactions characterise and govern the current state and fate of a living cell. The specificity of proteins is mainly determined by the relative affinities to each potential ligand. To investigate the consequences and potentials of ligands with increased specificity in comparison with ligands optimised solely for affinity, it was necessary to identify ligands that are optimised towards specificity instead of a barely optimised affinity to a given target.
View Article and Find Full Text PDF