Publications by authors named "Matthias Fellhauer"

An important prerequisite for ascertaining rational antibiotic prescribing is the availability and evaluation of antibiotic use data. In this study we report evolving trends of antibiotic use in German hospitals during the last decade.Using drug dispensing data from acute care hospital pharmacies, we calculated yearly antibiotic use density values for the period from 2012/13 through to 2021/22.

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Article Synopsis
  • Antimicrobial stewardship (AMS) programs improve antibiotic prescribing, necessitating regular monitoring of antibiotic use in pediatric hospitals, where the study focused on antibiotic consumption density (ACD) in 2020 across 113 German hospitals.
  • The median ACD was 26.7 DDD/100 patient days, with university hospitals showing higher rates, and oncology and intensive care units having the highest densities; overall, antibiotic use declined slightly from 2013-2020, but there were notable increases in "Watch" and "Reserve" category antibiotics.
  • The findings highlight significant variability in antibiotic prescribing practices and raise concerns about high cephalosporin usage and the need for AMS programs to address these issues in order to combat antimicrobial resistance.
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Background: There is much discussion about which measure or bundle of measures is most efficient in hospital antibiotic management programs, and it is often unknown which parts of such programs are readily available. The ABS International group conducted a survey to estimate the prevalence and characteristics of country-specific hospital antibiotic management programs and program components. This paper summarizes the results for Germany.

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