Seromucinous Cystadenoma Presenting as Endometriosis Complications in a 57-Year-Old Female: A Case Report.

Endometriosis should be considered when a female patient reports symptoms of severe pain/tenderness in the pelvic area associated with a frequent need for urination, bloating, vomiting, or nausea. Clinical suspicion is increased if the patient has a history of endometriosis. However, many patients with endometriosis can be asymptomatic, which is why physicians and providers must keep an open mind and have a broad differential.

Impact of fibrinogen and prothrombin complex concentrate on clotting time in a model of obstetric hemorrhage.

Study Objective: Determine the impact of varying doses of fibrinogen concentrate and 4-factor prothrombin complex concentrate on clotting time as measured by thromboelastometry in an in-vitro model of dilutional coagulopathy.

Design: In-Vitro Study.

Setting: Tertiary academic center.

The relationship between INTEM/HEPTEM coagulation time ratio and heparin plasma concentration in obstetric patients: an exploratory in vitro investigation.

Purpose: Unfractionated heparin continues to be one of the main agents used for thromboprophylaxis in obstetrics, which can complicate the placement of neuraxial anesthetics. In this study, we explored the relationship between a point-of-care coagulation test (thromboelastometry) and plasma heparin concentrations in vitro.

Methods: We obtained blood from consenting obstetric patients with uncomplicated pregnancies in their third trimester who were not in labour and had a specific hematocrit range.

Baseline parameters for non-activated rotational thromboelastometry tests with and without heparinase in healthy pregnant women at term gestation.

Objective: To determine the normal values for non-activated thromboelastometry parameters among pregnant women.

Design: Prospective, observational study.

Setting: Tertiary care hospital.

The impact of crystalloid versus colloid on coagulation as measured by thromboelastometry in term parturients: an in vitro study.

Objective: A pilot study to examine the impact of crystalloid versus albumin hemodilution on coagulation using thromboelastometry in pregnant patients.

Methods: This prospective, observational pilot study included seventy-six pregnant patients at term (≥37 weeks) without history of bleeding or clotting disorder or on anticoagulation. Blood was collected and diluted with either Plasma-Lyte or albumin at the following levels: 0%, 20%, 25%, 30%, 35%, 40%, 45%, 55%, 60%, 65%, 70%, 75%, 80%.

Thromboelastometry-guided neuraxial anesthesia in a parturient with severe thrombocytopenia due to large granular lymphocytic leukemia.

Severe thrombocytopenia (platelet count <50 000/μl) in pregnancy is uncommon and is generally considered a contraindication to neuraxial anesthesia. We present a case of a parturient who presented with severe thrombocytopenia secondary to bone marrow failure. After receiving platelet and cryoprecipitate transfusions to correct coagulopathy as verified by thromboelastometry, neuraxial anesthesia was safely utilized.

The effects of hemodilution on coagulation in term parturients: an study utilizing rotational thromboelastometry.

Objective: To examine the impact of hemodilution on components of blood coagulation using rotational thromboelastometry (ROTEM) in term parturients.

Methods: This is a prospective, observational pilot study including 35 healthy, parturients at term (≥37 weeks) without history of bleeding or clotting disorder or on medication affecting coagulation. Venous blood samples were collected and divided into specimen tubes to generate varying degrees of hemodilution with Plasma-Lyte (0%, 20%, 25%, 30%, 35%, 40%, 45%, 55%, 60%, 65%, 70%, 75%, 80%).