Publications by authors named "Matthew Sandre"
Article Synopsis
- Liquid silicone is an affordable injectable option for soft tissue enhancement, but it carries a risk of delayed granuloma formation linked to high levels of tumor necrosis factor-α.
- A case was reported involving persistent silicone granulomas after facial injections, which were successfully treated using tumor necrosis factor-α blockade.
- Both this case and prior studies suggest that this treatment is effective for managing foreign body granulomas caused by silicone.
Leukemia cutis represents infiltration of the skin by malignant leukocytes and typically presents as firm, red-brown papules and nodules. The bullous clinical subtype is considered a rare entity and can be a diagnostic challenge. This case describes a patient with bullous leukemia cutis mimicking vesiculobullous skin disease.
View Article and Find Full Text PDFMyeloid sarcoma (MS) is a rare extramedullary tumor of malignant myeloid cells often associated with acute myeloid leukemia. We report a case of a 17-year-old boy presenting with diffuse red-brown skin nodules ultimately diagnosed with the scarcely described disseminated, de novo MS. It is important for dermatologists to keep MS on their differential when assessing patients with disseminated red-brown nodules.
View Article and Find Full Text PDFWe present a patient with new-onset erythema nodosum leprosum months after successful treatment of her mid-borderline leprosy, which was likely triggered by a combination of antecedent influenza vaccination and upper respiratory tract infection.
View Article and Find Full Text PDFA Case of a Paediatric Patient With Allergic Contact Dermatitis to Benzoyl Peroxide.
J Cutan Med Surg
September 2018
Allergic contact dermatitis to benzoyl peroxide can occur in up to 6.5% of those with a history of exposure to this potential allergen. Conversely, irritant contact dermatitis is very common with benzoyl peroxide and can be differentiated from allergic contact dermatitis based on the patient's history and clinical signs and symptoms.
View Article and Find Full Text PDFArticle Synopsis
- Crusted scabies is a highly contagious skin condition influenced by factors like weakened immune response and nutritional deficiencies.
- The case involves a patient with a persistent rash, initially misdiagnosed due to similarities with other skin issues like psoriasis.
- After unsuccessful treatment with topical permethrin, oral ivermectin was given, leading to a swift improvement in the patient's skin condition.
Psoriatic Nail Changes Are Associated With Clinical Outcomes in Psoriatic Arthritis.
J Cutan Med Surg
October 2015
Article Synopsis
- Nail changes are common in patients with psoriatic arthritis (PsA), and this study explored how these changes relate to skin patches and joint issues.* -
- The research involved assessing 188 PsA patients through various dermatological evaluations and photography of their hands and nails.* -
- Findings indicated that higher joint inflammation levels were linked to specific nail changes, such as psoriasis around the nail area and certain nail conditions, particularly those on the same digit as affected joints.*
Psoriatic arthritis and nail changes: exploring the relationship.
Semin Arthritis Rheum
October 2014
Article Synopsis
- * A literature review of 21 articles showed that about 66% of PsA patients exhibit nail changes, but the specific types and associations of these changes differ significantly across studies.
- * The conclusion emphasizes the need for larger and more consistent studies to better understand the prevalence and nature of nail changes in patients with PsA due to the high variability in existing research findings.
Background: The replicative helicase in eukaryotic cells is comprised of minichromosome maintenance (Mcm) proteins 2 through 7 (Mcm2-7) and is a key target for regulation of cell proliferation. In addition, it is regulated in response to replicative stress. One of the protein kinases that targets Mcm2-7 is the Dbf4-dependent kinase Cdc7 (DDK).
View Article and Find Full Text PDF