Publications by authors named "Matthew Reschke"
Article Synopsis
- Epidural opioids, such as methadone and morphine, are used for managing acute postoperative pain, but this study investigates whether methadone provides better localized pain relief (segmental analgesia) than morphine.
- In the study, 13 healthy volunteers received epidural injections of either 4 mg of methadone or morphine and their pain tolerance was tested across different body regions for 24 hours.
- Results showed no significant difference in localized pain relief between the two drugs, although morphine resulted in longer-lasting analgesia and more systemic side effects compared to methadone, which had a better side effect profile.
Background: The optimal choice of vasopressor drugs for managing hypotension during neuraxial anaesthesia for Caesarean delivery is unclear. Although phenylephrine was recently recommended as a consensus choice, direct comparison of phenylephrine with vasopressors used in other healthcare settings is largely lacking. Therefore, we assessed this indirectly by collating data from relevant studies in this comprehensive network meta-analysis.
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