Submandibular gland injury and delayed airway compromise caused by a seat belt.

Isolated blunt injury to the submandibular gland (SMG) is rare owing to the protection afforded by the overlying mandible. Like other causes of submandibular swelling, glandular trauma can lead to life-threatening airway compromise, and this possibility should be considered in patients presenting with acute pain and fullness in the jaw and neck after trauma. We describe a patient with SMG disruption caused by a seat belt shoulder strap, discuss the diagnosis and treatment, and present a review of the literature.

Desmin ensheathment ratio as an indicator of vessel stability: evidence in normal development and in retinopathy of prematurity.

We developed a measure of pericyte/endothelial interaction, the desmin ensheathment ratio (DER), using the intermediate filament desmin as an indicator of pericyte ensheathment and have examined the DER in normal retinal vascular development and in the kitten retinopathy of prematurity (ROP) model. We also examined the role of mural cells in the pathogenesis of ROP. Postnatal day 1 to 45 kitten retinae were labeled for desmin, alpha-smooth muscle actin (SMA), and isolectin-B4.