Publications by authors named "Matthew P Blackwell"

Article Synopsis
  • Postgraduate residency training is vital to academic medicine in the U.S., relying on the ERAS platform and NRMP for matching applicants and programs, but rising applicants per spot have created matching challenges.
  • The 2020-2021 Match Cycle introduced a supplemental application system using preference signals/tokens, allowing applicants to indicate interest in specific programs, which showed positive results in specialties like otolaryngology and urology.
  • Neurosurgery adopted this signaling system for its residency applications starting in the 2022-2023 Cycle, providing applicants with 25 signals to enhance their chances of securing interviews and ultimately improve the match process.
View Article and Find Full Text PDF
Article Synopsis
  • - A 33-year-old female with a history of infiltrating astrocytoma developed obstructive hydrocephalus, requiring a ventriculoperitoneal (VP) shunt for treatment.
  • - She experienced non-specific symptoms that led to a shunt evaluation, where it was discovered that the shunt's distal catheter had migrated into the pleural space.
  • - Remarkably, the patient remained asymptomatic for two years after the migration, emphasizing the need for careful monitoring and management of VP shunt-related complications.
View Article and Find Full Text PDF

Background: This technical note presents a novel minimally invasive exoscope assisted coccygectomy to treat chronic refractory coccydynia. Traditional treatments often fail to provide adequate relief for this debilitating condition, prompting the need to explore surgical approaches.

Case Description: A 40-year-old female patient with persistent pain unresponsive to conservative treatments underwent this advanced procedure.

View Article and Find Full Text PDF

Skeletal insufficiency affects all individuals with Down syndrome (DS) or trisomy 21 and may alter bone strength throughout development due to a reduced period of bone formation and early attainment of peak bone mass compared to those in typically developing individuals. Appendicular skeletal deficits also appear in males before females with DS. In femurs of male Ts65Dn DS model mice, cortical deficits were pronounced throughout development, but trabecular deficits and Dyrk1a overexpression were transitory until postnatal day (P) 30, when there were persistent trabecular and cortical deficits and Dyrk1a was trending toward overexpression.

View Article and Find Full Text PDF

Skeletal insufficiency affects all individuals with Down syndrome (DS) or Trisomy 21 (Ts21) and may alter bone strength throughout development due to a reduced period of bone formation and early attainment of peak bone mass compared to typically developing individuals. Appendicular skeletal deficits also appear in males before females with DS. In femurs of male Ts65Dn DS model mice, cortical deficits were pronounced throughout development, but trabecular deficits and overexpression were transitory until postnatal day (P) 30 when there were persistent trabecular and cortical deficits and was trending overexpression.

View Article and Find Full Text PDF