Publications by authors named "Matthew Noneman"

Article Synopsis
  • Gastrointestinal pain and fatigue are key issues for patients with inflammatory bowel disease (IBD), with some experiencing abdominal pain even when their disease is inactive; Ojeok-san (OJS), a medicinal herb, shows potential in alleviating this pain but lacks research in IBD preclinical models.
  • * The study aimed to evaluate the analgesic effects of OJS and its potential for addiction, while also examining tumor necrosis factor alpha (TNFα) from macrophages as a factor in IBD-related pain.
  • * Results indicated that OJS effectively reduced pain responses in various IBD models without exhibiting rewarding properties or being influenced by TNFα levels from macrophages, suggesting its promise as a treatment for managing pain in IBD
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Cancer patients can develop visceral, somatic, and neuropathic pain, largely due to the malignancy itself and its treatments. Often cancer patients and survivors turn to the use of complementary and alternative medicine (CAM) to alleviate pain and fatigue. Thus, it is necessary to investigate how CAM therapies work as novel analgesics to treat cancer pain.

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