Publications by authors named "Matthew Laurence Stoll"
Objective: To evaluate the involvement of intraarticular (IA) infliximab (IFX) in the management of temporomandibular joint (TMJ) arthritis associated with juvenile idiopathic arthritis (JIA) that is refractory to systemic treatment and IA corticosteroid therapy.
Methods: Ours was a retrospective study of children with JIA who received IA IFX into the TMJ. The effectiveness of treatment on the progression of acute and chronic changes was assessed by a quantitative magnetic resonance imaging scoring system.
Objective: Rituximab (RTX) has been used to treat many pediatric autoimmune conditions. We investigated the safety and efficacy of RTX in a variety of pediatric autoimmune diseases, especially systemic lupus erythematosus (SLE).
Methods: Retrospective study of children treated with RTX.
Article Synopsis
- * A study reviewed 58 children receiving high-dose IFX, noting 9 serious adverse events and a few infusion reactions, but no severe anaphylactic cases occurred.
- * Significant improvements in disease activity were observed after one year of treatment, indicating high-dose IFX may be a safe and effective option for managing JIA, though further controlled studies are needed.