Publications by authors named "Matthew Lashmet"

Persistent and saturated oxygen distribution from perfusion media (i.e., blood, or cell culture media) to cells within cell-dense, metabolically-active biofabricated tissues is required to keep them viable.

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Corneal transplantation is the only option to cure corneal opacities. However, there is an imbalance between supply and demand of corneal tissues in the world. To solve the problem of corneal shortage, corneal xenotransplantation studies have been implemented in the past years using porcine corneas.

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Article Synopsis
  • CB2R receptors play a significant role in corneal wound healing, as their expression increases following corneal injury.
  • Activation of CB2R with the agonist JWH133 promotes cell movement in cultured bovine corneal epithelial cells but does not affect cell growth.
  • The study suggests that CB2R activation enhances signaling pathways connected to wound healing and that blocking these receptors delays the healing process.
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