Impact of acute sleep restriction on cerebrovascular reactivity and neurovascular coupling in young men and women.

Chronic exposure to shortened sleep is associated with increased risk of Alzheimer's disease and dementia. Previous studies show insufficient (, poor or fragmented) sleep impairs cerebrovascular reactivity to metabolic stress and may have a detrimental effect on the link between cerebral blood flow (CBF) and neural activity (, neurovascular coupling, NVC). The purpose of this study was to examine the effect of acute sleep restriction on CBF in response to a metabolic (carbon dioxide; CO) and a cognitive stressor.

Insights into the Effects of Zinc Doping on Structural Phase Transition of P2-Type Sodium Nickel Manganese Oxide Cathodes for High-Energy Sodium Ion Batteries.

P2-type sodium nickel manganese oxide-based cathode materials with higher energy densities are prime candidates for applications in rechargeable sodium ion batteries. A systematic study combining in situ high energy X-ray diffraction (HEXRD), ex situ X-ray absorption fine spectroscopy (XAFS), transmission electron microscopy (TEM), and solid-state nuclear magnetic resonance (SS-NMR) techniques was carried out to gain a deep insight into the structural evolution of P2-Na0.66Ni0.

Zero-Strain Na2FeSiO4 as Novel Cathode Material for Sodium-Ion Batteries.

A new cubic polymorph of sodium iron silicate, Na2FeSiO4, is reported for the first time as a cathode material for Na-ion batteries. It adopts an unprecedented cubic rigid tetrahedral open framework structure, i.e.

Enhancing the energy density of safer Li-ion batteries by combining high-voltage lithium cobalt fluorophosphate cathodes and nanostructured titania anodes.

Recently, Li-ion batteries have been heavily scrutinized because of the apparent incompatibility between safety and high energy density. This work report a high voltage full battery made with TiO2/Li3PO4/Li2CoPO4F. The Li2CoPO4F cathode and TiO2 anode materials are synthesized by a sol-gel and anodization methods, respectively.

Toward a stabilized lattice framework and surface structure of layered lithium-rich cathode materials with Ti modification.

Layered lithium-rich oxides have several serious shortcomings such as fast voltage fading and poor cyclic stability of energy density which greatly hinder their practical applications. Fabrication of a stable framework of layered lithium-rich oxides during charging-discharging is crucial for addressing the above problems. In this work, we show that Ti modification is a promising way to realize this target with bifunctional roles.

Lumbosacral epidural lipomatosis causing rapid onset cauda equina syndrome.

Spinal epidural lipomatosis (SEL) is a rare cause of cauda equina syndrome (CES), which must be diagnosed with MRI in conjunction with a high level of clinical suspicion. Most reported cases are associated with obesity, steroid use or are secondary to endocrinopathies, frequently present subacutely or chronically, and have been managed with both surgical decompression and non-operative measures. We describe an obese 55-year-old man with rapid onset CES secondary to idiopathic lumbosacral SEL which was managed successfully with surgical decompression.

Ten-year follow-up of a patient with Osler-Weber-Rendu syndrome and recurrent cerebral abscess secondary to pulmonary arteriovenous fistula.

In 1998, one of us (MJM) published an article discussing several patients with Osler-Weber-Rendu Syndrome or hereditary haemorrhagic telangiectasia with secondary cerebral complications. These were intracerebral haemorrhage, ischaemic infarct and intracerebral abscess. We outlined the background of the syndrome as well as its genotype and predicted an increasingly important role for genetic testing.