Publications by authors named "Matthew J Bruno"
Dermatol Ther (Heidelb)
October 2023
Article Synopsis
- Tapinarof cream 1% is a non-steroidal topical treatment confirmed by the FDA for plaque psoriasis in adults and currently being explored for children and atopic dermatitis.
- The PSOARING phase 3 trials show that tapinarof cream improves psoriasis symptoms significantly with a high number of patients (40.9%) achieving complete clearance of the disease.
- The treatment is generally well tolerated, with mild side effects like folliculitis and contact dermatitis, and patients reported favorable quality of life improvements.
J Drugs Dermatol
August 2023
Article Synopsis
- * The PSOARING phase 3 trials showed that tapinarof cream (1% applied once daily) was effective and well tolerated, with notable clearance rates (40.9%) after 52 weeks of ongoing use.
- * Adverse effects were generally mild, with folliculitis being the most common, leading to a low rate of discontinuation in the studies, making tapinarof a promising long-term treatment for psoriasis.
