Publications by authors named "Matthew Ha"
Clinical Relevance: Binocular visual acuity is an important index of functional performance. Optometrists need to know how binocular visual acuity is affected by aniseikonia, and whether reduced binocular visual acuity is a marker for aniseikonia.
Background: Aniseikonia, the perception of unequal image sizes between the eyes, can occur spontaneously or can be induced after different types of eye surgery, or trauma.
Evoked potentials (EP), measured using electroencephalographic (EEG) recordings provide an opportunity to monitor cognitive dysfunctions after neurological diseases or traumatic brain injury (TBI). The 4 week old piglet is an established model of paediatric TBI; therefore, healthy piglets were studied to establish feasibility of obtaining responses to auditory and visual stimuli. A secondary aim was to input the EEG data into a piglet computational model to localize the brain sources related to processing.
View Article and Find Full Text PDFArticle Synopsis
- T1R2 and T1R3 are G protein-coupled receptors that act as sweet taste receptors, with functionality differing across species.
- New World monkeys, like squirrel monkeys, cannot perceive many artificial sweeteners (e.g., aspartame, saccharin) but can respond to certain proteins (like thaumatin) at high concentrations.
- The study suggests that specific amino acid differences in the receptor contribute to the variations in sweet taste perception between squirrel monkeys and humans, influenced by their molecular structure.
The heterodimer of Tas1R2 and Tas1R3 is a broadly acting sweet taste receptor, which mediates mammalian sweet taste toward natural and artificial sweeteners and sweet-tasting proteins. Perception of sweet taste is a species-selective physiological process. For instance, artificial sweeteners aspartame and neotame taste sweet to humans, apes, and Old World monkeys but not to New World monkeys and rodents.
View Article and Find Full Text PDF