Publications by authors named "Matthew H Rim"

Article Synopsis
  • AJHP is posting accepted manuscripts online quickly after peer review, but these are not final versions and will be updated later.
  • The article aims to assist health-system pharmacists by providing updates on new drug approvals that can affect clinical practices and resource management.
  • A selection of 51 potential new drugs awaiting FDA approval is discussed, highlighting significant developments in treatments for rare diseases, cancers, and other conditions expected between late 2024 and mid-2025.
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Article Synopsis
  • AJHP is posting accepted manuscripts online promptly to speed up publication, even before final formatting and author proofing are completed.
  • The article highlights the essential role of health-system pharmacists in managing drug formularies and resources, focusing on upcoming drug approvals that could impact clinical practices.
  • Anticipated drug approvals include new treatments for various cancers and rare diseases, with several innovative therapies and delivery methods under review by the FDA for the period of late 2024 to mid-2025.
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Article Synopsis
  • Health-system pharmacists are vital for managing drug formularies and clinical programs, and this article provides updates on upcoming drug approvals to aid their work.
  • The article reviews drug approvals expected between Q2 2024 and Q1 2025, focusing on those that may significantly impact healthcare settings and are awaiting FDA approval.
  • New therapies are being developed for cancers and rare diseases, alongside drugs addressing conditions like diabetes and chronic obstructive pulmonary disease.
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Purpose: The establishment of a new outpatient pharmacy provided a strategic opportunity to repurpose and convert an existing outpatient pharmacy into a closed-door mail-order pharmacy within a health system. This article describes the steps taken to successfully make this change and evaluates the impact.

Summary: The mail-order pharmacy conversion project was divided into 3 phases: phase 1 (before conversion) from July through August 2022, phase 2 (conversion) from October through November 2022, and phase 3 (after conversion) from December 2022 through February 2023.

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Article Synopsis
  • The report analyzes historical pharmaceutical spending in the U.S. and predicts factors influencing future expenditures, especially in nonfederal hospitals and clinics, for the year 2024.
  • In 2023, total drug spending reached $722.5 billion, a 13.6% increase from the previous year, driven by heightened utilization, new drug approvals, and moderate price increases.
  • For 2024, overall drug spending is projected to rise by 10.0% to 12.0%, with clinics and hospitals expecting an increase of 11.0% to 13.0%, highlighting the ongoing impact of specialty and cancer drugs on spending.
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Purpose: Health-system pharmacists play a crucial role in monitoring the pharmaceutical pipeline to manage formularies, allocate resources, and optimize clinical programs for new therapies. This article aims to support pharmacists by providing periodic updates on new and anticipated novel drug approvals.

Summary: Selected drug approvals anticipated in the 12-month period covering the first quarter of 2024 through the fourth quarter of 2024 are reviewed.

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Purpose: Health-system pharmacists play a crucial role in monitoring the pharmaceutical pipeline to manage formularies, allocate resources, and optimize clinical programs for new therapies. This article aims to support pharmacists by providing updates on new and anticipated novel drug approvals.

Summary: Selected drug approvals anticipated in the 12-month period covering the fourth quarter of 2023 through the third quarter of 2024 are reviewed.

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Purpose: Health-system pharmacists play a crucial role in monitoring the pharmaceutical pipeline to manage formularies, allocate resources, and optimize clinical programs for new therapies. This article aims to support pharmacists by sharing new and anticipated novel drug approvals.

Summary: Selected drug approvals anticipated in the 12-month period covering the second quarter of 2023 through the first quarter of 2024 are reviewed.

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Article Synopsis
  • The report analyzes historical pharmaceutical spending trends and predicts future drug expenditures in the US, particularly in nonfederal hospitals and clinics for 2023.
  • It reviews factors affecting drug spending such as new drug approvals, patent expirations, and policy changes, concluding that specialty and cancer medications will significantly impact future costs.
  • In 2022, drug spending rose by 9.4% to $633.5 billion, with a forecasted 6.0% increase in overall spending for 2023.
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Article Synopsis
  • The report analyzes historical trends in pharmaceutical spending in the U.S. and predicts factors impacting future costs, particularly in nonfederal hospitals and clinics for 2022.
  • In 2021, drug spending increased by 7.7% to total $576.9 billion, driven by higher utilization, prices, and new drug approvals, with adalimumab being the top costing drug.
  • For 2022, overall drug spending is projected to grow by 4.0% to 6.0%, with clinics and hospitals expecting increases of 7.0% to 9.0% and 3.0% to 5.0%, respectively.
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Article Synopsis
  • The report analyzed historical patterns of pharmaceutical spending in the U.S. and aimed to predict growth for 2021, focusing on nonfederal hospitals and clinics.
  • Drug expenditures grew by 4.9% in 2020, mainly due to increased utilization and new drugs, with the top drugs being adalimumab, apixaban, and insulin glargine.
  • For 2021, an overall increase in prescription drug spending of 4% to 6% is expected, with clinics forecasting a 7% increase, driven by new product approvals and ongoing effects of the COVID-19 pandemic.
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Purpose: Direct and indirect costs related to the growth of specialty pharmacy services and the insurance navigation process for specialty clinic patients are discussed, and development and implementation of a pharmacy-driven and system-wide prior authorization (PA) processing center within a health system are described.

Summary: Expensive specialty drugs require PA. Due to the concentration of specialists, health systems with multiple specialties experience higher PA burden and resulting care delays.

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Purpose: To report historical patterns of pharmaceutical expenditures, to identify factors that may influence future spending, and to predict growth in drug spending in 2020 in the United States, with a focus on the nonfederal hospital and clinic sectors.

Methods: Historical patterns were assessed by examining data on drug purchases from manufacturers using the IQVIA National Sales Perspectives database. Factors that may influence drug spending in hospitals and clinics in 2020 were reviewed, including new drug approvals, patent expirations, and potential new policies or legislation.

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Objective: To describe the system-wide implementation of integrated electronic prior authorization (ePA) and its impact within a centralized prior authorization (PA) department in an academic health system.

Setting: Prescription drugs have been among the fastest growing areas of health care and continue to advance; therefore, costs associated with medications are continually rising. Pharmacy benefit managers implement tools such as PAs in an effort to manage costs.

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Purpose: The development and implementation of centralized mail-order pharmacy services in an academic healthcare system are described.

Summary: The use of mail-order pharmacy services continues to increase, as mail-order services offer patient benefits such as reduced copayments and improved clinical outcomes. Prior to undertaking an initiative to improve its mail-order pharmacy services, the University of Utah Health system's pharmacy department offered decentralized mail-order pharmacy services at all of its retail pharmacies, but there was no standardized process for processing mail-order prescriptions or providing phone support to mail-order patients.

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Purpose: Historical trends and factors likely to influence future pharmaceutical expenditures are discussed, and projections are made for drug spending in 2019 in nonfederal hospitals, clinics, and overall (all sectors).

Methods: Drug expenditure data through calendar year 2018 were obtained from the IQVIA National Sales Perspectives database and analyzed. New drug approvals, patent expirations, and other factors that may influence drug spending in hospitals and clinics in 2019 were also reviewed.

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Purpose: The implementation and quality assessment of a pharmacy services call center (PSCC) for outpatient pharmacies and specialty pharmacy services within an academic health system are described.

Summary: Prolonged wait times in outpatient pharmacies or hold times on the phone affect the ability of pharmacies to capture and retain prescriptions. To support outpatient pharmacy operations and improve quality, a PSCC was developed to centralize handling of all outpatient and specialty pharmacy calls.

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Purpose: The development and implementation of a centralized, comprehensive, refill authorization (CCRA) program within an academic health system are described.

Summary: In order to improve continuity of care for our medically complicated patients, ambulatory pharmacy services developed and implemented a highly coordinated CCRA program for multiple community clinics within the system. To implement the CCRA program, we centralized the refill-request intake process to the Pharmacy Ambulatory Clinical Care Center (PAC).

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Purpose: The development and implementation of a systemwide specialty pharmacy program in an academic healthcare system are described.

Summary: Although the system's pharmacy department had developed specialty pharmacy services for patients with certain conditions, it was necessary to expand and standardize those services to meet the needs of all specialty clinics because (1) many of the clinics had experienced an increased volume of prior-authorization requests due to the introduction of new specialty drugs, (2) the dispensing pharmacies were operating at maximum capacity due to the previous decentralization of specialty pharmacy operations, and (3) payers had sent notice that they would require accreditation of the specialty pharmacy program as a condition of participation in their specialty pharmacy networks. To ensure standardization of services and successful preparation for increasing numbers of specialty prescriptions, all specialty pharmacy services were centralized to the healthcare system's Pharmacy Ambulatory Clinical Care Center (PAC(3)).

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