Publications by authors named "Matthew G Dimond"
ESC Heart Fail
September 2024
Article Synopsis
- The study investigates the use of guideline-directed medical therapy (GDMT) in patients who survive cardiogenic shock (CS) with heart failure and reduced left ventricular ejection fraction (HFrEF) based on data from a single-center shock registry.
- Among 520 patients treated for CS, 185 (35.6%) had HFrEF upon discharge, with a median age of 64 years; 41% experienced shock due to acute myocardial infarction, while the rest had heart failure-related shock.
- At discharge, a substantial portion of patients were prescribed GDMT, including beta-blockers (78%), ACE inhibitors/ARBs (58%), and mineralocorticoid receptor antagonists (55%), yet 10
JACC Heart Fail
March 2024
Article Synopsis
- - Heart failure (HF) is usually classified based on left ventricular ejection fraction (LVEF), but this method relies on arbitrary cutpoints that might not reflect the physiological complexities of the condition.
- - A recent review by the Heart Failure Collaboratory analyzed various clinical trials and found that many HF treatments work effectively across a wide range of LVEF values, although their specific effects can differ depending on the LVEF level.
- - Moving forward, it is proposed that HF classification focuses on whether LVEF is reduced or not, while promoting further research to test new treatments across the entire LVEF spectrum.
