Publications by authors named "Matthew Farleigh"

Article Synopsis
  • Thermogalvanic devices can turn low-grade waste heat (<200 °C) into electricity through an electrochemical reaction driven by a temperature difference.
  • The study focuses on cobalt (II/III) sarcophagine compounds, examining how different solvents affect their thermogalvanic performance.
  • Results show that the Seebeck coefficient, a measure of voltage generated, varies significantly with solvent type, indicating that the ionic charge from surrounding groups enhances the electrochemical process in specific low-dielectric solvents.
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Background: Multi-tracer PET/SPECT imaging enables different modality tracers to be present simultaneously, allowing multiple physiological processes to be imaged in the same subject, within a short time-frame. Fluorine-18 and technetium-99m, two commonly used PET and SPECT radionuclides, respectively, possess different emission profiles, offering the potential for imaging one in the presence of the other. However, the impact of the presence of each radionuclide on scanning the other could be significant and lead to confounding results.

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Positron Emission Tomography (PET) imaging with antibody-based contrast agents frequently uses the radioisotopes [Cu]Cu and [Zr]Zr. The macrobicyclic chelator commonly known as sarcophagine (sar) is ideal for labeling receptor-targeted biomolecules with [Cu]Cu. The siderophore chelator, desferrioxamine-B (dfo), has been widely used to incorporate [Zr]Zr into antibodies.

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