Publications by authors named "Matthew Edward Ryan"

Article Synopsis
  • Tensin 1 is a focal adhesion adaptor protein that interacts with the extracellular matrix and cytoskeleton, and forms a family with three other Tensin proteins now known to influence cell signaling related to cancer development.
  • Evidence shows that Tensin proteins, especially Tensin 1-3, are linked to both tumor suppressor and oncogenic roles in various cancers, with specific effects depending on the tumor subtype.
  • The review discusses how these proteins interact with the tumor suppressor DLC1 and how their roles in cancer biology reflect on potential clinical implications and therapeutic strategies.
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