Publications by authors named "Matthew Edward Ryan"
Article Synopsis
- Tensin 1 is a focal adhesion adaptor protein that interacts with the extracellular matrix and cytoskeleton, and forms a family with three other Tensin proteins now known to influence cell signaling related to cancer development.
- Evidence shows that Tensin proteins, especially Tensin 1-3, are linked to both tumor suppressor and oncogenic roles in various cancers, with specific effects depending on the tumor subtype.
- The review discusses how these proteins interact with the tumor suppressor DLC1 and how their roles in cancer biology reflect on potential clinical implications and therapeutic strategies.
